(alffaR,gamaS)-gama-[(3-Carboxy-1-ocsopropyl)amino]-alffa-methyl-[1,1'-deuffenyl]-4-Asid pentanoic 4- ethyl Ester Calsium Halen

(alffaR,gamaS)-gama-[(3-Carboxy-1-ocsopropyl)amino]-alffa-methyl-[1,1'-deuffenyl]-4-asid pentanoic 4- halen calsiwm ethyl ester

Rhif CAS:1369773-39-6

[Cyfystyron]

(2S,4R)-5-(Deuffenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-ester ethyl asid methylpentanoic, halen calsiwm(2: 1)

(alffaR,gamaS)-gama-[(3-Carboxy-1-ocsopropyl)amino]-alffa-methyl-[1,1'-deuffenyl]-4-asid pentanoic 4- halen calsiwm ethyl ester (2: 1)

AHU-377 halen hemicalsiwm (2:1)

Calsiwmbis(4-{[(1S,3R)-1-([1,1'-deuffenyl]-4-ylmethyl)-4-ethoxy-3-methyl{10 }}oxobutyl] amino} 1oxobutanoate);

[Melting point] >140 gradd (Rhag.)

[Dwysedd] 1.24g/cm3 ar 20 gradd

[Pwysau anwedd] 0.001Pa ar 20 gradd

[Tymer storio.] -20 gradd

[Hoddedd] DMSO (Ychydig, Wedi'i Gynhesu), Methanol (Ychydig)

[Ffurflen] powdr

[Lliw] gwyn i beige

[Logp] -0.66-2.9 ar 20 gradd a ph2-7

[FDA UNII] 8F45HCQ47Q

[Defnyddiau]

Mae sacubitril yn gyffur gwrthhypertensive a ddefnyddir mewn cyfuniad â valsartan. Mae'r cyffur cyfun, valsartan/sacubitril, a elwir yn ystod treialon fel LCZ696 ac sy'n cael ei farchnata dan yr enw brand, Entresto, yn driniaeth ar gyfer methiant y galon.

Tagiau poblogaidd: (alffa, gamma) -gama-[(3-carboxy-1-ocsopropyl)amino]-alffa-methyl-[1,1'-deuffenyl]-4-asid pentanoic 4- halen calsiwm ethyl ester, Tsieina, gweithgynhyrchwyr, cyflenwyr, ffatri, cyfanwerthu, arfer